In the present study and followed by conventional method, an efficient and design synthesis a novel series of 5-Amino-1, 3-diphenyl-1H-pyrazole-4-carbonitrile derivatives. These derivatives can be obtained by Phenyl hydrazine, aromatic aldehydes and malononitrile in presence of base catalyst Ph₃P in ethanol as a solvent at reflux. All the newly obtained derivatives were evaluated by the advanced spectroscopic analysis such as ¹HNMR, ¹³CNMR and LCMS and structural determination of titled analogous were calculated by elemental analysis. In addition to the newly synthesised compounds were examined by their anti-microbial activity.

In the present study and followed by conventional method, an efficient and design synthesis a novel series of 5-amino-3-phenylisoxazole-4-carbonitrile derivatives. These derivatives can be obtained by substituted aromatic aldehyde, malononitrile and hydroxylamine hydrochloride in presence of Lews acid catalyst ceric ammonium sulphate in isopropyl alcohol as a solvent at reflux. All the titled analogous were evaluated by the advanced spectroscopic analysis such as ¹HNMR, ¹³CNMR and LCMS and structural determination of titled analogous were calculated by elemental analysis. In addition to the newly synthesized compounds were examined by their anti-microbial activity.

A simple sensitive spectrophotometric method for the determination of cerium (IV) involving ion-pair complexation. It starts with the introduction to cerium, literature survey regarding the various methods reported for cerium including spectrophotometric methods. In this method, cerium (IV) oxidizes catechol to quinone, which is quite reactive and can be attracted by a variety of nucleophiles, which prompted to use p-anisidine to attack the quinone formed via the oxidation of catechol by cerium (IV) in acidic medium producing coloured compound having maximum absorbance at 565nm and stabilized through an ion-pair formation with [Ce(OH₂)₂Cl₄]. The method obeys the Lambert – Beer’s law in the range 1.732-173.285mg ml^-1 with a straight line having slope 0.0020 and intercept 0.0594. Molar absorptivity, correlation coefficient and Sandell’s sensitivity values were calculated and found to be 2.77 x 10³Lmol^-1cm^-1, 0.992 and 0.0505mgcm^-2 respectively.A probable reaction mechanism along with experimental stoichiometry of the ion-pair are indicated. The proposed method was applied for the determination of cerium in high purity rare earth carbonates and synthetic mixtures.